Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 7/20 | 0.45 |
| ▸ | ACHE | P22303 | 7/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385998 | 0.75 | MEN1 (0.51) | MEN1KMT2ACRHBPCRHR2ALDH1A1 | |
| SCHEMBL14540454 | 0.72 | MEN1 (0.74) | MEN1KMT2ACRHBPCRHR2ALDH1A1 | |
| SCHEMBL9781306 | 0.70 | MEN1 (0.52) | MEN1KMT2ACRHBPCRHR2ALDH1A1 | |
| SCHEMBL19772465 | 0.70 | CHRM2 (0.51) | MEN1KMT2ACRHBPCRHR2ALDH1A1 | |
| SCHEMBL6583786 | 0.70 | MEN1 (0.62) | MEN1KMT2ACRHBPCRHR2ALDH1A1 | |
| SCHEMBL6583793 | 0.70 | MEN1 (0.62) | MEN1KMT2ACRHBPCRHR2BCHE | |
| SCHEMBL14276937 | 0.70 | MEN1 (0.48) | MEN1KMT2ACRHBPCRHR2ALDH1A1 | |
| SCHEMBL735118 | 0.69 | SLC6A4 (0.68) | MEN1KMT2ACRHBPCRHR2CHRM2 | |
| SCHEMBL8796368 | 0.69 | PTGES (0.56) | MEN1KMT2ACRHBPCRHR2ALDH1A1 | |
| SCHEMBL15118580 | 0.69 | MEN1 (0.61) | MEN1KMT2ACRHBPCRHR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996024353-A1 | METHODS OF TREATING OR PREVENTING PSYCHIATRIC DISORDERS | ELI LILLY AND COMPANY (US) | 1996-08-15 | — | — | WO | disclosed |