Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | ACACB | O00763 | 8/20 | 0.39 |
| ▸ | ACACA | Q13085 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948277 | 0.81 | ALOX5 (0.78) | ALOX5EPHX2ACACBACACAHPGD | |
| SCHEMBL15122396 | 0.81 | ALOX5 (0.61) | ALOX5EPHX2HPGDMAPK1TSHR | |
| SCHEMBL15122395 | 0.81 | ALOX5 (0.61) | ALOX5EPHX2HPGDMAPK1TSHR | |
| SCHEMBL13140100 | 0.80 | ALOX5 (0.83) | ALOX5EPHX2HPGD | |
| Atreleuton SCHEMBL504818 | 0.78 | ALOX5 (1.00) | ALOX5EPHX2ACACBACACA | |
| Atreleuton SCHEMBL2107799 | 0.78 | ALOX5 (1.00) | ALOX5EPHX2ACACBACACA | |
| Atreleuton SCHEMBL2108309 | 0.78 | ALOX5 (1.00) | ALOX5EPHX2ACACBACACA | |
| SCHEMBL8304903 | 0.77 | ALOX5 (0.65) | ALOX5EPHX2ACACBHPGDKDM4E | |
| SCHEMBL2872801 | 0.74 | ALOX5 (0.73) | ALOX5EPHX2 | |
| SCHEMBL895799 | 0.74 | ALOX5 (0.52) | ALOX5EPHX2ACACBACACAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996032377-A1 | LIPOXYGENASE AND CYCLOOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-10-17 | — | — | WO | disclosed |