Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7611507 | 0.82 | ALDH1A1 (0.61) | SIGMAR1MAPTSMN1; SMN2PTGS2LMNA | |
| SCHEMBL517975 | 0.82 | ALDH1A1 (0.61) | SIGMAR1MAPTSMN1; SMN2PTGS2LMNA | |
| SCHEMBL9737497 | 0.82 | ALDH1A1 (0.61) | SIGMAR1MAPTSMN1; SMN2PTGS2LMNA | |
| SCHEMBL6641309 | 0.82 | ALDH1A1 (0.61) | SIGMAR1MAPTSMN1; SMN2PTGS2LMNA | |
| SCHEMBL26639967 | 0.81 | ALDH1A1 (0.49) | SIGMAR1MAPTCTDSP1L3MBTL1LMNA | |
| SCHEMBL11394554 | 0.81 | ALDH1A1 (0.49) | SIGMAR1MAPTCTDSP1L3MBTL1LMNA | |
| SCHEMBL10895512 | 0.80 | ALDH1A1 (0.48) | SIGMAR1MAPTSMN1; SMN2CTDSP1L3MBTL1 | |
| SCHEMBL8807613 | 0.79 | ALDH1A1 (0.49) | MAPTSMN1; SMN2CTDSP1L3MBTL1PTGS2 | |
| SCHEMBL10556254 | 0.79 | HTT (0.57) | SIGMAR1MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL11739927 | 0.78 | MAPT (0.57) | SIGMAR1MAPTSMN1; SMN2PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996009294-A1 | SUBSTITUTED HETEROAROMATIC COMPOUNDS AND THEIR USE IN MEDICINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-03-28 | — | — | WO | disclosed |