SCHEMBL8933773

SCHEMBL8933773

CC(c1ccc(OCc2ccccc2)cc1)N(O)C(N)=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 6/20 1.00
PARP10 Q53GL7 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9474724 0.99 ALOX5 (0.97) ALOX5PARP10
Ammonia Solution, Strong SCHEMBL9473339 0.99 ALOX5 (0.97) ALOX5PARP10
SCHEMBL9475019 0.99 ALOX5 (0.97) ALOX5PARP10
SCHEMBL9475027 0.94 ALOX5 (0.88) ALOX5
Tetrylammonium SCHEMBL9377970 0.93 ALOX5 (0.86) ALOX5
SCHEMBL9473489 0.89 ALOX5 (0.80) ALOX5
SCHEMBL9474936 0.88 ALOX5 (0.79) ALOX5
SCHEMBL7713248 0.88 ALOX5 (0.78) ALOX5
SCHEMBL9474500 0.87 ALOX5 (0.77) ALOX5PARP10
SCHEMBL9473784 0.87 ALOX5 (0.77) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996032377-A1 LIPOXYGENASE AND CYCLOOXYGENASE INHIBITING COMPOUNDS ABBOTT LABORATORIES (US) 1996-10-17 WO disclosed
US-5516789-A NON-STEROIDAL ANTIINFLAMMATORY AGENTS ABBOTT LABORATORIES (US) 1996-05-14 US disclosed
EP-0292699-B1 Urea based lipoxygenase inhibiting compounds ABBOTT LAB (US) 1994-03-23 EP disclosed
US-5185363-A Administering for treatment of inflammatory diseases ABBOTT LABORATORIES (US) 1993-02-09 US disclosed
EP-0292699-A2 Urea based lipoxygenase inhibiting compounds ABBOTT LABORATORIES (US) 1988-11-30 EP disclosed