Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959525 | 0.97 | GABRA1 (0.36) | GABRA1GABRB2FPR2CYP3A4CYP2C9 | |
| SCHEMBL8933627 | 0.95 | CNR2 (0.35) | GABRA1GABRB2FPR2CYP3A4CYP2C9 | |
| SCHEMBL8933657 | 0.94 | GABRA1 (0.35) | GABRA1GABRB2FPR2CYP3A4CYP2C9 | |
| SCHEMBL8933738 | 0.94 | GABRA1 (0.34) | GABRA1GABRB2FPR2CYP3A4CYP2C9 | |
| SCHEMBL8933846 | 0.94 | GABRA1 (0.34) | GABRA1GABRB2FPR2CYP3A4CYP2C9 | |
| SCHEMBL8933755 | 0.94 | GABRA1 (0.34) | GABRA1GABRB2FPR2CYP3A4CYP2C9 | |
| SCHEMBL8933840 | 0.94 | GABRA1 (0.34) | GABRA1GABRB2FPR2CYP3A4CYP2C9 | |
| SCHEMBL8933815 | 0.93 | KDM1A (0.37) | GABRA1GABRB2FPR2CYP3A4CYP2C9 | |
| SCHEMBL19985396 | 0.93 | GABRA1 (0.38) | GABRA1GABRB2FPR2CYP2C9 | |
| SCHEMBL8959543 | 0.93 | CNR2 (0.33) | GABRA1GABRB2CYP3A4CYP2C9FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |