Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934137 | 0.84 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL8934007 | 0.82 | PTGS2 (0.54) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL9233734 | 0.81 | PTGS2 (0.57) | PTGS2PTGS1CA1CA2CA4 | |
| SCHEMBL8933960 | 0.81 | PTGS2 (0.53) | PTGS2PTGS1CA1CA2CA4 | |
| SCHEMBL8933816 | 0.79 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL8933915 | 0.78 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL8933813 | 0.78 | PTGS2 (0.55) | PTGS2PTGS1CA1CA2CA4 | |
| SCHEMBL6341956 | 0.74 | PTGS2 (0.76) | PTGS2PTGS1CA1CA2CA4 | |
| SCHEMBL8933921 | 0.73 | PTGS2 (1.00) | PTGS2PTGS1CA1CA2CA4 | |
| SCHEMBL6977030 | 0.72 | PTGS2 (0.66) | PTGS2PTGS1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996009304-A1 | BENZOPYRANOPYRAZOLYL DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-28 | — | — | WO | claimed |