Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 6/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18061084 | 0.70 | MAOB (0.51) | NISCHMAOBMIFMAOAPTPN1 | |
| SCHEMBL30290792 | 0.69 | GRK2 (0.43) | NISCHMAOBMIFMAOAPTPN1 | |
| SCHEMBL2172925 | 0.69 | GRK2 (0.43) | NISCHMAOBMIFMAOAPTPN1 | |
| SCHEMBL8933833 | 0.68 | MAPT (0.32) | ENPP1 | |
| SCHEMBL2490828 | 0.68 | CHRM2 (0.50) | NISCHMAOBMIFCHRM2CHRM4 | |
| SCHEMBL10423403 | 0.67 | MAOB (0.40) | MAOBMAOAPTPN1PSMB5NOTUM | |
| SCHEMBL4514403 | 0.66 | KDM4E (0.41) | NISCHMAOBMIFCHRM2CHRM4 | |
| SCHEMBL5613767 | 0.62 | EPHX2 (0.50) | MAOBESR1ESR2EPHX2 | |
| SCHEMBL9533688 | 0.62 | ATM (0.46) | NISCHMAOBMIFMAOAPTPN1 | |
| SCHEMBL3312793 | 0.62 | MAOB (0.36) | NISCHMAOBMIFMAOAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996009304-A1 | BENZOPYRANOPYRAZOLYL DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-28 | — | — | WO | claimed |