Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KHK | P50053 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933988 | 0.69 | MAPT (0.35) | MAPTMEN1KMT2AENPP1LMNA | |
| SCHEMBL8933931 | 0.68 | NISCH (0.35) | ENPP1 | |
| SCHEMBL4503571 | 0.67 | KDM4E (0.38) | MAPTMEN1POLBKMT2ALMNA | |
| SCHEMBL4585151 | 0.61 | ALOX5 (0.39) | MAPTMEN1KMT2AENPP1LMNA | |
| SCHEMBL4079696 | 0.60 | CYP2A6 (0.42) | MAPTPOLBLMNACYP1A2CYP2C9 | |
| SCHEMBL10902564 | 0.60 | MAPT (0.41) | MAPTPOLBLMNACYP1A2CYP2C9 | |
| SCHEMBL14280970 | 0.59 | ENPP1 (0.47) | MAPTENPP1NPSR1ELANEKDM4E | |
| SCHEMBL731681 | 0.59 | KDM4E (0.46) | MAPTPOLBLMNACYP1A2CYP2C9 | |
| SCHEMBL25286620 | 0.59 | MAPT (0.34) | MAPTMEN1KMT2AENPP1LMNA | |
| SCHEMBL3296726 | 0.59 | CFTR (0.58) | MAPTKMT2ALMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996009304-A1 | BENZOPYRANOPYRAZOLYL DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-28 | — | — | WO | claimed |