Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 4/20 | 0.44 |
| ▸ | TYMP | P19971 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933927 | 1.00 | HPRT1 (0.44) | HPRT1TYMPCYP3A4FGFR1SLC22A6 | |
| SCHEMBL8934012 | 0.87 | HPRT1 (0.32) | HPRT1 | |
| SCHEMBL8934022 | 0.81 | — | — | |
| SCHEMBL6896277 | 0.65 | CYP3A4 (0.47) | HPRT1TYMPCYP3A4 | |
| SCHEMBL6897604 | 0.64 | CYP3A4 (0.46) | HPRT1TYMPCYP3A4FGFR1SLC22A6 | |
| SCHEMBL6903597 | 0.63 | HPRT1 (0.59) | HPRT1TYMPCYP3A4 | |
| SCHEMBL6901396 | 0.63 | HPRT1 (0.59) | HPRT1TYMPCYP3A4 | |
| SCHEMBL6901392 | 0.63 | HPRT1 (0.59) | HPRT1TYMPCYP3A4 | |
| SCHEMBL6901990 | 0.63 | HPRT1 (0.59) | HPRT1TYMPCYP3A4 | |
| SCHEMBL6903599 | 0.63 | HPRT1 (0.59) | HPRT1TYMPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996009307-A1 | PURINE AND 8-AZAPURINE DERIVATIVES SUITABLE TO THE THERAPEUTIC TREATMENT OF AIDS | ISTITUTO SUPERIORE DI SANITA' (IT) | 1996-03-28 | — | — | WO | disclosed |