Fluoride

Fluoride

SCHEMBL8934075

C=C(C)C(=O)NC(CC)C(C)N(C)C.F

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.41
RXFP1 Q9HBX9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1635161 0.79 TGFBR1 (0.46) TGFBR1
SCHEMBL34096 0.76 TGFBR1 (0.44) TGFBR1RXFP1
Hydrochloric Acid SCHEMBL7945240 0.74 TGFBR1 (0.43) TGFBR1
SCHEMBL9139203 0.74 TGFBR1 (0.40) TGFBR1RXFP1
SCHEMBL6470862 0.73 TSHR (0.50)
SCHEMBL6703621 0.73 TGFBR1 (0.42) TGFBR1
SCHEMBL554944 0.72 TGFBR1 (0.48) TGFBR1RXFP1
SCHEMBL491239 0.72 TGFBR1 (0.44) TGFBR1RXFP1
SCHEMBL17555031 0.72 KAT2B (0.44) TGFBR1
Hydrochloric Acid SCHEMBL7926572 0.72 MEN1 (0.34) TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996022761-A1 FLUORIDE ION RELEASING DENTAL MATERIALS INDIANA UNIVERSITY FOUNDATION (US) 1996-08-01 WO disclosed