SCHEMBL8934129

SCHEMBL8934129

CCCCCC1CCC(c2ccc(-c3ccc(-c4ccc(CC)c(F)c4F)cc3)cc2F)CC1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.37
OPRL1 P41146 13/20 0.35
FFAR4 Q5NUL3 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
RARB P10826 2/20 0.32
RARA P10276 1/20 0.32
RARG P13631 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8934198 0.99 DGAT1 (0.36) DGAT1OPRL1FFAR4GAAMAPT
SCHEMBL8960372 0.97 DGAT1 (0.35) DGAT1OPRL1FFAR4GAAMAPT
SCHEMBL8961087 0.96 DGAT1 (0.35) DGAT1OPRL1FFAR4GAAMAPT
SCHEMBL8934108 0.93 OPRL1 (0.35) DGAT1OPRL1FFAR4GAAMAPT
SCHEMBL8934112 0.93 OPRL1 (0.35) DGAT1OPRL1FFAR4GAAMAPT
SCHEMBL8934144 0.93 OPRL1 (0.35) DGAT1OPRL1FFAR4GAAMAPT
SCHEMBL8934178 0.92 DGAT1 (0.38) DGAT1OPRL1FFAR4MAPT
SCHEMBL8933996 0.92 RARB (0.35) DGAT1OPRL1FFAR4GAAMAPT
SCHEMBL8934134 0.92 OPRL1 (0.34) DGAT1OPRL1FFAR4GAAMAPT
SCHEMBL8934322 0.92 RARB (0.35) DGAT1OPRL1FFAR4GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed