Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 20/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933966 | 0.85 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL8933882 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL8933905 | 0.76 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL6344383 | 0.74 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL8933767 | 0.72 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL8933968 | 0.72 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL8933879 | 0.72 | PTGS2 (0.82) | PTGS2PTGS1 | |
| SCHEMBL8933871 | 0.72 | PTGS2 (0.52) | PTGS2PTGS1ABCB11 | |
| SCHEMBL8934166 | 0.72 | PTGS2 (0.84) | PTGS2PTGS1 | |
| SCHEMBL8860032 | 0.70 | PTGS2 (0.55) | PTGS2PTGS1ABCB11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996009304-A1 | BENZOPYRANOPYRAZOLYL DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-28 | — | — | WO | claimed |