Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.53 |
| ▸ | TERT | O14746 | 2/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 8-Methoxyflavone SCHEMBL26180800 | 0.86 | ALDH1A1 (0.74) | ALDH1A1CYP3A4MAPTHPGDKDM4E | |
| SCHEMBL8934630 | 0.81 | ALDH1A1 (0.60) | LCKALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL8934574 | 0.81 | ALDH1A1 (0.60) | LCKALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL311766 | 0.80 | ALDH1A1 (0.66) | ALDH1A1CYP3A4MAPTHPGDKDM4E | |
| 8,2'-Dimethoxyflavone SCHEMBL516353 | 0.78 | ALDH1A1 (1.00) | ALDH1A1CYP3A4MAPTHPGDKDM4E | |
| SCHEMBL5796867 | 0.75 | TNKS (0.71) | ALDH1A1CYP3A4MAPTHPGDKDM4E | |
| SCHEMBL28592427 | 0.74 | ALDH1A1 (0.64) | ALDH1A1CYP3A4MAPTHPGDKDM4E | |
| SCHEMBL12835531 | 0.73 | CYP1A2 (0.54) | LCKALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL21801245 | 0.73 | ABCB1 (0.58) | ALDH1A1CYP3A4MAPTHPGDKDM4E | |
| SCHEMBL30744133 | 0.73 | ABCB1 (0.58) | ALDH1A1CYP3A4MAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |