Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380526 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDLMNAPOLB | |
| SCHEMBL5457898 | 0.71 | ALDH1A1 (0.81) | ALDH1A1MAPTLMNAEPHX1NPC1 | |
| SCHEMBL8611590 | 0.70 | ALDH1A1 (0.84) | ALDH1A1MAPTHPGDLMNAPOLB | |
| SCHEMBL7597743 | 0.69 | POLB (0.67) | ALDH1A1HPGDLMNAPOLBALOX12 | |
| SCHEMBL9376144 | 0.69 | MAPT (0.38) | ALDH1A1MAPTPOLBNPC1RAB9A | |
| SCHEMBL9376377 | 0.68 | MAPT (0.40) | ALDH1A1MAPTLMNAPOLBNPC1 | |
| SCHEMBL9379324 | 0.68 | MAPT (0.40) | ALDH1A1MAPTLMNAPOLBRXFP1 | |
| SCHEMBL5383053 | 0.68 | EPHX1 (0.68) | ALDH1A1HPGDLMNAPOLBALOX12 | |
| SCHEMBL28892777 | 0.68 | ALDH1A1 (0.82) | ALDH1A1MAPTHPGDLMNAPOLB | |
| SCHEMBL4875873 | 0.67 | AOC3 (0.59) | ALDH1A1HPGDLMNAMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030350-A1 | AMIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |