Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23861286 | 0.74 | NQO1 (0.56) | HSD17B3SMN1; SMN2ACHENPC1LMNA | |
| SCHEMBL8372531 | 0.73 | HSD17B3 (0.62) | HSD17B3MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6481670 | 0.71 | MAOB (0.46) | ALBMAOBMAPTKMT2AMEN1 | |
| SCHEMBL6482983 | 0.71 | MAOB (0.45) | ALBMAOBMAPTKMT2AMEN1 | |
| SCHEMBL5459900 | 0.70 | CA12 (0.61) | MAOBHSD17B3ACHEALDH1A1HPGD | |
| SCHEMBL18138409 | 0.70 | NQO1 (0.58) | HSD17B3MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL30486066 | 0.70 | CA12 (0.61) | MAOBHSD17B3ACHEALDH1A1HPGD | |
| SCHEMBL66891 | 0.69 | MAOA (0.74) | MAOBHSD17B3KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL29474940 | 0.69 | MAOA (0.74) | MAOBHSD17B3KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL24486980 | 0.69 | NPC1 (0.50) | MAOBHSD17B3MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |