Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 9/20 | 0.82 |
| ▸ | CSNK2B | P67870 | 9/20 | 0.82 |
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.82 |
| ▸ | GABRP | O00591 | 4/20 | 0.67 |
| ▸ | GABRD | O14764 | 4/20 | 0.67 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.67 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.67 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.67 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.67 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.67 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.67 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.67 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.67 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.67 |
| ▸ | GABRE | P78334 | 4/20 | 0.67 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.67 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.67 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.67 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.67 |
| ▸ | FYN | P06241 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15265120 | 0.89 | CSNK2A2 (0.80) | CSNK2A2CSNK2BCSNK2A1GABRPGABRD | |
| SCHEMBL8934505 | 0.85 | CYP1A1 (0.69) | CSNK2A2CSNK2BCSNK2A1FYNESR2 | |
| SCHEMBL5320080 | 0.84 | KDM4E (0.81) | CSNK2A2CSNK2BCSNK2A1FYNESR2 | |
| SCHEMBL4990151 | 0.81 | GABRP (1.00) | CSNK2A2CSNK2BCSNK2A1GABRPGABRD | |
| SCHEMBL30960382 | 0.80 | TNKS (0.71) | CSNK2A2CSNK2BCSNK2A1FYNESR2 | |
| SCHEMBL1744293 | 0.80 | TNKS (0.71) | CSNK2A2CSNK2BCSNK2A1FYNESR2 | |
| SCHEMBL29435863 | 0.80 | CSNK2A2 (0.81) | CSNK2A2CSNK2BCSNK2A1CYP1A1CYP1B1 | |
| SCHEMBL26117897 | 0.80 | CSNK2A2 (0.81) | CSNK2A2CSNK2BCSNK2A1CYP1A1CYP1B1 | |
| SCHEMBL4988784 | 0.79 | MAPT (0.77) | CSNK2A2CSNK2BCSNK2A1GABRPGABRD | |
| SCHEMBL18613228 | 0.79 | FYN (1.00) | CSNK2A2CSNK2BCSNK2A1FYNESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |