Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | PKM | P14618 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934620 | 0.80 | NPC1 (0.70) | SMN1; SMN2RAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL24066037 | 0.72 | KDM4E (0.59) | SMN1; SMN2RAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL9375682 | 0.71 | MAPT (0.53) | LMNASMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL9570185 | 0.71 | KDM4E (0.68) | SMN1; SMN2RAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL1818150 | 0.71 | LMNA (0.60) | LMNASMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL8934514 | 0.70 | KMT2A (0.46) | LMNASMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL12329335 | 0.69 | KDM4E (0.65) | SMN1; SMN2RAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL4000661 | 0.69 | LMNA (0.61) | LMNASMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL4000484 | 0.69 | LMNA (0.57) | LMNARAB9AMAPTNPC1CYP19A1 | |
| SCHEMBL30354914 | 0.68 | LMNA (0.60) | LMNARAB9AMAPTCYP19A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030350-A1 | AMIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |