Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 5/20 | 0.39 |
| ▸ | FNTB | P49356 | 5/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934705 | 1.00 | ALDH1A1 (0.40) | ALDH1A1FNTAFNTBPGGT1BKCNK3 | |
| SCHEMBL7996716 | 0.91 | ALDH1A1 (0.47) | ALDH1A1FNTAFNTBKMT2ACYP1A2 | |
| SCHEMBL7996714 | 0.91 | ALDH1A1 (0.47) | ALDH1A1FNTAFNTBKMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL7995505 | 0.90 | ALDH1A1 (0.46) | ALDH1A1FNTAFNTBKMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL7995503 | 0.90 | ALDH1A1 (0.46) | ALDH1A1FNTAFNTBKMT2ACYP1A2 | |
| SCHEMBL7993171 | 0.83 | FNTA (0.48) | FNTAFNTBPGGT1BKMT2AMAPT | |
| SCHEMBL7995119 | 0.83 | FNTA (0.48) | FNTAFNTBPGGT1BKMT2AMAPT | |
| SCHEMBL7993175 | 0.83 | FNTA (0.48) | FNTAFNTBPGGT1BKMT2AMAPT | |
| SCHEMBL8000774 | 0.82 | KMT2A (0.47) | ALDH1A1FNTAFNTBKCNK3KCNK9 | |
| SCHEMBL8000772 | 0.82 | KMT2A (0.47) | ALDH1A1FNTAFNTBKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030014-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | claimed |
| WO-1996030014-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | disclosed |