Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4379833 | 0.93 | AOC3 (0.36) | AOC3HRH4HRH3HDAC1 | |
| SCHEMBL4379648 | 0.91 | AKT2 (0.33) | — | |
| SCHEMBL4384967 | 0.74 | CYSLTR2 (0.33) | ALOX5 | |
| SCHEMBL4394318 | 0.73 | SLC6A4 (0.33) | HRH3 | |
| SCHEMBL9119383 | 0.70 | CYP19A1 (0.43) | — | |
| SCHEMBL9119464 | 0.69 | CYP19A1 (0.46) | HRH3 | |
| SCHEMBL4376567 | 0.68 | LMNA (0.34) | HRH3 | |
| SCHEMBL14414196 | 0.68 | SLC6A4 (0.49) | — | |
| SCHEMBL4383673 | 0.67 | CA1 (0.36) | — | |
| SCHEMBL9641597 | 0.67 | HRH1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | claimed |