Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28139905 | 0.66 | — | — | |
| SCHEMBL8934790 | 0.64 | LMNA (0.43) | LMNAPDGFRBPDGFRAKDM4EALDH1A1 | |
| Iodide SCHEMBL28806915 | 0.62 | MAPK1 (0.32) | PDE5A | |
| SCHEMBL14770739 | 0.61 | LMNA (0.36) | LMNAKDM4EALDH1A1TP53NPSR1 | |
| SCHEMBL22272517 | 0.61 | GRM1 (0.44) | LMNAPDE5AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL18379791 | 0.60 | MCHR1 (0.37) | LMNAKDM4EALDH1A1TP53NPSR1 | |
| SCHEMBL18714955 | 0.60 | MCHR1 (0.37) | LMNAKDM4EALDH1A1TP53NPSR1 | |
| SCHEMBL21466550 | 0.60 | MCHR1 (0.37) | LMNAKDM4EALDH1A1TP53NPSR1 | |
| SCHEMBL19055333 | 0.60 | MCHR1 (0.37) | LMNAKDM4EALDH1A1TP53NPSR1 | |
| SCHEMBL18379792 | 0.60 | MCHR1 (0.37) | LMNAKDM4EALDH1A1TP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | claimed |