Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.31 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934989 | 0.99 | GAA (0.38) | GAAMAPTOPRL1MEN1KMT2A | |
| SCHEMBL8961868 | 0.96 | GAA (0.34) | GAAMAPTOPRL1MEN1KMT2A | |
| SCHEMBL8962078 | 0.95 | GAA (0.36) | GAAMAPTOPRL1MEN1KMT2A | |
| SCHEMBL15581195 | 0.91 | GAA (0.37) | GAAMAPTOPRL1MEN1KMT2A | |
| SCHEMBL8934845 | 0.91 | OPRL1 (0.38) | MAPTOPRL1MEN1KMT2AMAPK1 | |
| SCHEMBL15043577 | 0.91 | OPRL1 (0.40) | GAAMAPTOPRL1MEN1KMT2A | |
| SCHEMBL8934142 | 0.90 | DGAT1 (0.37) | GAAMAPTOPRL1DGAT1 | |
| SCHEMBL4401705 | 0.89 | CYP2C9 (0.39) | GAAMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL8934339 | 0.89 | DGAT1 (0.37) | GAAMAPTOPRL1DGAT1 | |
| SCHEMBL22277193 | 0.88 | CYP2C9 (0.38) | GAAMAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |