Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.76 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.76 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | PNP | P00491 | 1/20 | 0.76 |
| ▸ | HTT | P42858 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.76 |
| ▸ | NT5E | P21589 | 2/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.64 |
| ▸ | PDE2A | O00408 | 1/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fludarabine SCHEMBL1697072 | 1.00 | LMNA (0.76) | LMNAPDE4DPDE3ATP53PNP | |
| Cladribine SCHEMBL2050327 | 0.93 | LMNA (0.72) | LMNAPDE4DPDE3ATP53PNP | |
| SCHEMBL15623873 | 0.87 | LMNA (0.76) | LMNAPDE4DPDE3ATP53PNP | |
| SCHEMBL1470361 | 0.87 | LMNA (0.76) | LMNAPDE4DPDE3ATP53PNP | |
| SCHEMBL5982283 | 0.87 | LMNA (0.76) | LMNAPDE4DPDE3ATP53PNP | |
| SCHEMBL23982169 | 0.87 | LMNA (0.76) | LMNAPDE4DPDE3ATP53PNP | |
| SCHEMBL976990 | 0.87 | LMNA (0.76) | LMNAPDE4DPDE3ATP53PNP | |
| SCHEMBL5982273 | 0.87 | LMNA (0.76) | LMNAPDE4DPDE3ATP53PNP | |
| SCHEMBL5790133 | 0.87 | LMNA (0.76) | LMNAPDE4DPDE3ATP53PNP | |
| SCHEMBL976991 | 0.87 | LMNA (0.76) | LMNAPDE4DPDE3ATP53PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595826-A4 | 2'-FLUORO-2-SUBSTITUTED ADENINYL ARABINOSIDES AS ANTI-CANCER AGENTS | SOUTHERN RES INST (US) | 1996-01-10 | — | — | EP | disclosed |
| EP-0595826-A1 | 2'-FLUORO-2-SUBSTITUTED ADENINYL ARABINOSIDES AS ANTI-CANCER AGENTS | Southern Research Institute (US) | 1994-05-11 | — | — | EP | disclosed |