⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7609201 | 0.82 | — | — | |
| SCHEMBL6907679 | 0.78 | — | — | |
| SCHEMBL10456316 | 0.76 | — | — | |
| SCHEMBL1273422 | 0.73 | — | — | |
| SCHEMBL10896564 | 0.72 | — | — | |
| SCHEMBL4340354 | 0.71 | — | — | |
| SCHEMBL6664707 | 0.70 | — | — | |
| SCHEMBL11285015 | 0.69 | — | — | |
| SCHEMBL1677860 | 0.69 | TSHR (0.39) | — | |
| SCHEMBL10874823 | 0.69 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455585-B1 | Unsaturated urea polysiloxanes | CIBA GEIGY AG (CH) | 1994-03-23 | — | — | EP | claimed |
| EP-0455585-A1 | Unsaturated urea polysiloxanes | CIBA-GEIGY AG (CH) | 1991-11-06 | — | — | EP | claimed |
| US-5480946-A | CONTACT LENSES | CIBA GEIGY CORPORATION (US) | 1996-01-02 | — | — | US | disclosed |
| EP-0291452-B1 | Terminal polyvinyl functional macromers, polymers thereof and contact lenses made therefrom | CIBA GEIGY AG (CH) | 1994-06-01 | — | — | EP | disclosed |
| EP-0455585-B1 | Unsaturated urea polysiloxanes | CIBA GEIGY AG (CH) | 1994-03-23 | — | — | EP | disclosed |
| EP-0311566-B1 | THERMOTROPIC BIPHILIC HYDROGELS AND HYDROPLASTICS | CIBA-GEIGY AG (CH) | 1993-03-24 | — | — | EP | disclosed |
| US-5147923-A | Water-swellable random copolymers of N, N-dimethylacrylamide and (cyclo)aliphatic or aromatic acrylic esters having low cloud points | CIBA-GEIGY CORPORATION (US) | 1992-09-15 | — | — | US | disclosed |
| US-5104954-A | Swellable random copolymers of N,N-dimethylacrylamide and acrylic esters having reversible cloud points; for heat activated sunscreens | CIBA-GEIGY CORPORATION (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0455585-A1 | Unsaturated urea polysiloxanes | CIBA-GEIGY AG (CH) | 1991-11-06 | — | — | EP | disclosed |
| US-5057560-A | Thermotropic copolymer hydrogels from N,N-dimethylacrylamide and methoxy-ethyl (meth) acrylate | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |
| US-4923906-A | Rigid, gas-permeable polysiloxane contact lenses | CIBA-GEIGY CORPORATION (US) | 1990-05-08 | — | — | US | disclosed |
| EP-0351364-A2 | Dimethylacrylamide-copolymer hydrogels with high oxygen permeability | CIBA-GEIGY AG (CH) | 1990-01-17 | — | — | EP | disclosed |
| US-4837289-A | CONTACT LENSES | CIBA-GEIGY CORPORATION (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0311566-A2 | Thermotropic biphilic hydrogels and hydroplastics | CIBA-GEIGY AG (CH) | 1989-04-12 | — | — | EP | disclosed |
| EP-0291452-A2 | Terminal polyvinyl functional macromers, polymers thereof and contact lenses made therefrom | CIBA-GEIGY AG (CH) | 1988-11-17 | — | — | EP | disclosed |