Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.60 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.60 |
| ▸ | HTR3B | O95264 | 1/20 | 0.60 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.60 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.60 |
| ▸ | HTR3A | P46098 | 1/20 | 0.60 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.60 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoclidine SCHEMBL1542430 | 0.81 | GLA (0.74) | CHRNA7HTR3EHTR3BCHRNB2CHRNA4 | |
| Benzoclidine SCHEMBL1542330 | 0.81 | GLA (0.74) | CHRNA7HTR3EHTR3BCHRNB2CHRNA4 | |
| Benzoclidine SCHEMBL342347 | 0.81 | GLA (0.74) | CHRNA7HTR3EHTR3BCHRNB2CHRNA4 | |
| SCHEMBL14685645 | 0.75 | CHRNA7 (1.00) | CHRNA7HTR3EHTR3BCHRNB2CHRNA4 | |
| SCHEMBL14678608 | 0.75 | CHRNA7 (1.00) | CHRNA7HTR3EHTR3BCHRNB2CHRNA4 | |
| SCHEMBL14678609 | 0.75 | CHRNA7 (1.00) | CHRNA7HTR3EHTR3BCHRNB2CHRNA4 | |
| SCHEMBL11896515 | 0.74 | GLA (0.58) | CHRNA7HTR3EHTR3BCHRNB2CHRNA4 | |
| SCHEMBL372949 | 0.73 | CHRNA7 (1.00) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL373197 | 0.73 | CHRNA7 (1.00) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL372135 | 0.73 | CHRNA7 (1.00) | CHRNA7BCHEACHECHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030054-A1 | 99mTc - LABELLED SEROTONIN RECEPTOR BINDING SUBSTANCES | MALLINCKRODT MEDICAL, INC. (US) | 1996-10-03 | — | — | WO | disclosed |