Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17378166 | 0.76 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1LMNAMEN1MAPT | |
| SCHEMBL3884112 | 0.73 | CYP19A1 (0.40) | ALDH1A1L3MBTL1LMNAMEN1MAPT | |
| SCHEMBL19889394 | 0.65 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1LMNAMEN1MAPT | |
| Oxirane SCHEMBL7625198 | 0.65 | MAPT (0.61) | ALDH1A1L3MBTL1MEN1MAPTKMT2A | |
| Fluoride SCHEMBL10704561 | 0.64 | MEN1 (0.89) | ALDH1A1L3MBTL1LMNAMEN1MAPT | |
| Fluoride SCHEMBL20497199 | 0.64 | MEN1 (0.89) | ALDH1A1L3MBTL1LMNAMEN1MAPT | |
| Fluoride SCHEMBL27330616 | 0.64 | — | — | |
| SCHEMBL3036428 | 0.63 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1LMNAMEN1MAPT | |
| Dioxane SCHEMBL29124568 | 0.63 | MAPT (0.57) | ALDH1A1L3MBTL1LMNAMEN1MAPT | |
| SCHEMBL940896 | 0.62 | ALDH1A1 (0.76) | ALDH1A1L3MBTL1LMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630261-A4 | NEW CYCLODEXTRINS AND NEW FORMULATED DRUGS. | AUSTRALIAN COMMERCIAL RESEARCH (AU) | 1996-11-06 | — | — | EP | disclosed |
| EP-0630261-A1 | NEW CYCLODEXTRINS AND NEW FORMULATED DRUGS | AUSTRALIAN COMMERCIAL RESEARCH & DEVELOPMENT LIMITED (AU) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993017711-A1 | NEW CYCLODEXTRINS AND NEW FORMULATED DRUGS | AUSTRALIAN COMMERCIAL RESEARCH & DEVELOPMENT LIMITED (AU) | 1993-09-16 | — | — | WO | disclosed |