Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 8/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935242 | 0.81 | MAOB (0.51) | FFAR1NPC1RAB9ALTA4H | |
| SCHEMBL8935237 | 0.81 | MAOB (0.51) | FFAR1NPC1RAB9ALTA4H | |
| SCHEMBL8935234 | 0.79 | FFAR1 (0.51) | FFAR1NPC1RAB9APPARAPPARG | |
| SCHEMBL7144602 | 0.78 | FFAR1 (0.50) | FFAR1PPARAPPARGS1PR1S1PR3 | |
| SCHEMBL8935294 | 0.78 | MAOB (0.51) | NPC1RAB9APPARAPPARG | |
| SCHEMBL8935318 | 0.78 | SCN3A (0.53) | — | |
| SCHEMBL8935303 | 0.77 | MAOB (0.54) | S1PR1S1PR5 | |
| SCHEMBL8935258 | 0.77 | MAOB (0.54) | — | |
| SCHEMBL8935354 | 0.77 | MAOB (0.55) | FFAR1 | |
| SCHEMBL8935383 | 0.76 | MAOB (0.57) | FFAR1S1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |