SCHEMBL8935285

SCHEMBL8935285

CC(N)(Cc1ccc(OCc2ccccc2Cl)cc1)C(N)=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.56
MAOA P21397 1/20 0.56
NR4A2 P43354 2/20 0.54
MAPT P10636 2/20 0.48
TP53 P04637 1/20 0.48
GAA P10253 1/20 0.48
ADAM17 P78536 1/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
HTT P42858 1/20 0.47
RAD52 P43351 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
RAB9A P51151 2/20 0.47
PPARG P37231 1/20 0.46
PPARD Q03181 1/20 0.46
PPARA Q07869 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8935304 0.87 MAOB (0.53) MAOBMAOANR4A2MAPTTP53
SCHEMBL8935443 0.85 MAOB (0.60) MAOBCYP1A2CYP2C19
SCHEMBL27309675 0.83 PARP10 (0.57) MAOBMAOANR4A2MAPTGAA
Hydrochloric Acid SCHEMBL27353104 0.82 PARP10 (0.56) MAOBMAOANR4A2MAPTGAA
SCHEMBL28510234 0.82 MAOB (0.57) MAOBMAOANR4A2KMT2ANPSR1
SCHEMBL27311683 0.81 PPARG (0.53) MAOBNR4A2MAPTHTTPPARG
SCHEMBL28502984 0.80 HPGD (0.57) MAPTTP53MEN1KMT2AHTT
SCHEMBL8935328 0.79 PKM (0.61) MAOBMAOA
SCHEMBL8935293 0.78 MAOB (0.53) MAOBMAOANR4A2MAPTTP53
SCHEMBL8935289 0.78 MAOB (0.51) MAOBMAOANR4A2MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5502079-A TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS FARMITALIA CARLO ERBA S.R.L. (IT) 1996-03-26 US disclosed