Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346982 | 0.84 | EPHX1 (0.61) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL7346978 | 0.84 | EPHX1 (0.61) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL8302412 | 0.84 | EPHX1 (0.61) | EPHX1ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL28589046 | 0.83 | EPHX1 (0.59) | EPHX1ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL28589045 | 0.83 | EPHX1 (0.59) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL8935463 | 0.82 | EPHX1 (0.53) | PPARGPPARAEPHX1ALPIPKM | |
| Acetic Acid SCHEMBL6692778 | 0.80 | ALPI (0.56) | SLC6A4EPHX1ALPIPKMPTGS1 | |
| SCHEMBL24098559 | 0.78 | SLC6A4 (0.61) | SLC6A4PPARGPPARAHAO1EPHX1 | |
| SCHEMBL17079480 | 0.75 | MAPT (0.49) | EPHX1MEN1KMT2AALPIPKM | |
| SCHEMBL8935323 | 0.74 | FFAR1 (0.56) | PPARGPPARAEPHX1MMP2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |