Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | ANPEP | P15144 | 3/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.45 |
| ▸ | LAP3 | P28838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346978 | 0.93 | EPHX1 (0.61) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL8302412 | 0.93 | EPHX1 (0.61) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL7346982 | 0.93 | EPHX1 (0.61) | EPHX1ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL28589045 | 0.91 | EPHX1 (0.59) | EPHX1ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL28589046 | 0.91 | EPHX1 (0.59) | EPHX1ALPIPKMPTGS1XIAP | |
| Acetic Acid SCHEMBL6692778 | 0.88 | ALPI (0.56) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL8935392 | 0.84 | FFAR1 (0.62) | FFAR1PPARGPPARA | |
| SCHEMBL17079480 | 0.82 | MAPT (0.49) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL8935323 | 0.82 | FFAR1 (0.56) | EPHX1FFAR1PPARGPPARAMMP2 | |
| SCHEMBL8935344 | 0.82 | SLC6A4 (0.60) | EPHX1FFAR1ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |