Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935507 | 0.88 | MAOB (0.55) | MAOBFFAR1MRGPRX4KDM4ENPC1 | |
| SCHEMBL8935253 | 0.88 | MAOB (0.54) | MAOBPARP10MAOA | |
| SCHEMBL7398078 | 0.88 | MAOB (0.54) | MAOBMAOA | |
| SCHEMBL8935380 | 0.86 | MAOB (0.57) | MAOBFFAR1MRGPRX4ALDH1A1 | |
| SCHEMBL8935288 | 0.81 | MAOB (0.51) | MAOBFFAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8935370 | 0.81 | MAOB (0.50) | MAOBFFAR1KDM4ESMN1; SMN2 | |
| SCHEMBL8935234 | 0.78 | FFAR1 (0.51) | FFAR1NPC1RAB9A | |
| SCHEMBL8935313 | 0.78 | SCN3A (0.53) | MAOBPARP10 | |
| SCHEMBL8935289 | 0.78 | MAOB (0.51) | MAOBNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8935352 | 0.76 | MAOB (0.55) | MAOBFFAR1KDM4EMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |