Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935358 | 0.88 | MAOB (0.53) | MAOBRAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL8935253 | 0.87 | MAOB (0.54) | MAOB | |
| SCHEMBL7398078 | 0.87 | MAOB (0.54) | MAOBPKM | |
| SCHEMBL8935380 | 0.85 | MAOB (0.57) | MAOBALDH1A1FFAR1MRGPRX4 | |
| SCHEMBL8935288 | 0.81 | MAOB (0.51) | MAOBRAB9ASMN1; SMN2NPC1FFAR1 | |
| SCHEMBL8935370 | 0.78 | MAOB (0.50) | MAOBSMN1; SMN2KDM4EFFAR1 | |
| SCHEMBL8935234 | 0.77 | FFAR1 (0.51) | RAB9ANPC1FFAR1 | |
| SCHEMBL8935289 | 0.77 | MAOB (0.51) | MAOBRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL8935313 | 0.77 | SCN3A (0.53) | MAOB | |
| SCHEMBL8935352 | 0.75 | MAOB (0.55) | MAOBKDM4EFFAR1SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |