Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439130 | 1.00 | MAOB (0.55) | MAOBMAOASCN9A | |
| SCHEMBL7398312 | 1.00 | MAOB (0.55) | MAOBMAOASCN9A | |
| SCHEMBL27621008 | 0.90 | BCHE (0.55) | MAOBMAOASCN9A | |
| SCHEMBL1070410 | 0.88 | BCHE (0.54) | — | |
| SCHEMBL7394895 | 0.88 | BCHE (0.54) | — | |
| SCHEMBL7396992 | 0.88 | BCHE (0.54) | — | |
| SCHEMBL19450068 | 0.86 | POLB (0.51) | — | |
| SCHEMBL3073641 | 0.86 | MMP9 (0.60) | — | |
| SCHEMBL5133922 | 0.86 | MAOB (0.76) | MAOBMAOASCN9A | |
| SCHEMBL15195013 | 0.84 | SCN9A (0.76) | MAOBMAOASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |
| US-5391577-A | Active on central nervous system; antiepileptic agents | FARMITALIA CARLO ERBA S R L (IT) | 1995-02-21 | — | — | US | disclosed |
| US-5236957-A | Antiepileptic agents | FARMITALIA CARLO ERBA SRL (IT) | 1993-08-17 | — | — | US | disclosed |