Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935239 | 0.86 | MAOB (0.63) | MAOBPARP10MAOASCN9ANR4A2 | |
| SCHEMBL1534880 | 0.78 | MAOB (0.69) | MAOBPARP10MAOASCN9AFFAR1 | |
| Hydrochloric Acid SCHEMBL3501614 | 0.77 | MAOB (0.60) | MAOBPARP10MAOASCN9ANR4A2 | |
| Hydrochloric Acid SCHEMBL3499320 | 0.77 | MAOB (0.60) | MAOBPARP10MAOASCN9ANR4A2 | |
| SCHEMBL8935372 | 0.77 | MAOB (0.54) | MAOBPARP10MAOASCN9ANR4A2 | |
| SCHEMBL8935278 | 0.76 | MAOB (0.60) | MAOBMAOAFFAR1NR4A2 | |
| SCHEMBL8935251 | 0.76 | MAOB (0.58) | MAOBPARP10MAOASCN9ANR4A2 | |
| SCHEMBL16552360 | 0.76 | MAOB (1.00) | MAOBMAOANR4A2 | |
| SCHEMBL22950617 | 0.75 | EPHX1 (0.53) | MAOA | |
| SCHEMBL7512093 | 0.75 | EPHX1 (0.53) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |