Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935296 | 0.87 | ALOX5 (0.60) | MAOBMAOA | |
| SCHEMBL8935376 | 0.86 | MAOB (0.60) | MAOBNR4A2 | |
| SCHEMBL8935310 | 0.81 | MAOB (0.55) | MAOBPARP10SCN9A | |
| SCHEMBL4540328 | 0.79 | MAOB (0.62) | MAOBPARP10MAOASCN9ANR4A2 | |
| SCHEMBL9129876 | 0.79 | MAOB (0.71) | MAOBPARP10MAOASCN9ANR4A2 | |
| SCHEMBL7396562 | 0.79 | MAOB (0.71) | MAOBPARP10MAOASCN9ANR4A2 | |
| SCHEMBL8935232 | 0.78 | FFAR1 (0.51) | — | |
| SCHEMBL7398540 | 0.78 | MAOB (0.55) | MAOBPARP10MAOASCN9ANR4A2 | |
| SCHEMBL9129081 | 0.78 | MAOB (0.55) | MAOBPARP10MAOASCN9ANR4A2 | |
| SCHEMBL8935286 | 0.76 | MAOB (0.54) | MAOBMAOANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |