Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HRH1 | P35367 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935416 | 1.00 | AOC3 (0.46) | AOC3LMNARIPK1MEN1KMT2A | |
| SCHEMBL9063549 | 0.82 | AOC3 (0.42) | AOC3LMNARIPK1MEN1KMT2A | |
| SCHEMBL4742956 | 0.81 | RIPK1 (0.44) | AOC3LMNARIPK1HTR2AHRH1 | |
| SCHEMBL8089713 | 0.79 | AOC3 (0.42) | AOC3LMNARIPK1MEN1KMT2A | |
| SCHEMBL8094239 | 0.79 | AOC3 (0.42) | AOC3LMNARIPK1MEN1KMT2A | |
| SCHEMBL27254251 | 0.79 | AOC3 (0.42) | AOC3LMNARIPK1MEN1KMT2A | |
| SCHEMBL27254426 | 0.79 | AOC3 (0.42) | AOC3LMNARIPK1MEN1KMT2A | |
| SCHEMBL6738852 | 0.78 | AOC3 (0.41) | AOC3LMNARIPK1MEN1KMT2A | |
| SCHEMBL18697443 | 0.78 | AOC3 (0.44) | AOC3LMNARIPK1HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL11128441 | 0.76 | AOC3 (0.43) | AOC3LMNARIPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441116-B1 | Process and intermediates for the manufacture of optically active chroman derivatives | ASAHI DENKA KOGYO KK (JP) | 1995-04-05 | — | — | EP | claimed |
| US-5262552-A | Optically active compounds and intermediates thereof, and process for manufacturing same | ASAHI DENKA KOGYO K.K. (JP) | 1993-11-16 | — | — | US | claimed |
| US-5233056-A | Optically active chroman derivatives and intermediates thereof, and process for manufacturing same | ASAHI DENKA KOGYO K.K. (JP) | 1993-08-03 | — | — | US | claimed |
| EP-0441116-A2 | Process and intermediates for the manufacture of optically active chroman derivatives | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1991-08-14 | — | — | EP | claimed |
| JP-3215481-A | — | — | None | — | — | JP | disclosed |
| US-5504219-A | Optically active compounds and intermediates thereof, and process for manufacturing same | ASAHI DENKA KOGYO K.K. (JP) | 1996-04-02 | — | — | US | disclosed |
| EP-0441116-B1 | Process and intermediates for the manufacture of optically active chroman derivatives | ASAHI DENKA KOGYO KK (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5352845-A | Process for manufacture of optically active saturated compounds | ASAHI DENKA KOGYO K.K. (JP) | 1994-10-04 | — | — | US | disclosed |
| US-5262552-A | Optically active compounds and intermediates thereof, and process for manufacturing same | ASAHI DENKA KOGYO K.K. (JP) | 1993-11-16 | — | — | US | disclosed |
| US-5233056-A | Optically active chroman derivatives and intermediates thereof, and process for manufacturing same | ASAHI DENKA KOGYO K.K. (JP) | 1993-08-03 | — | — | US | disclosed |
| JP-H03215481-A | OPTICALLY ACTIVE CHROMAN-2-ETHANOL DERIVATIVE AND ITS INTERMEDIATE | ASAHI DENKA KOGYO KK | 1991-09-20 | — | — | JP | disclosed |
| EP-0441116-A2 | Process and intermediates for the manufacture of optically active chroman derivatives | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1991-08-14 | — | — | EP | disclosed |