SCHEMBL893544

SCHEMBL893544

COCCc1nc2c(N)nc3ccccc3c2n1CCOCCN(C)C(=O)C1CCCCC1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30200834 1.00 TLR7 (0.53) TLR7
SCHEMBL6031026 0.85 TLR7 (0.57) TLR7
SCHEMBL4792794 0.84 TLR7 (0.37) TLR7
SCHEMBL4336407 0.83 TLR7 (0.55) TLR7
SCHEMBL4331154 0.83 TLR7 (0.56) TLR7
SCHEMBL676401 0.82 TLR7 (0.60) TLR7
SCHEMBL29852303 0.82 TLR7 (0.60) TLR7
SCHEMBL31006041 0.82 TLR8 (0.55) TLR7
SCHEMBL17783025 0.81 TLR7 (0.51) TLR7
SCHEMBL5736958 0.81 TLR7 (0.56) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023097237-A2 CYTOSOLIC BACTERIAL PATHOGENS ATTENUATED FOR SPREAD FROM TUMORS AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-06-01 WO claimed
US-20040067975-A1 Amido ether substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2004-04-08 US claimed
US-6664265-B2 Amido ether substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2003-12-16 US claimed
US-20030187016-A1 Amido ether substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2003-10-02 US claimed
US-20250152703-A1 COMPOSITIONS FOR STIMULATION OF MAMMALIAN INNATE IMMUNE RESISTANCE TO PATHOGENS THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2025-05-15 US disclosed
US-12201684-B2 Compositions for stimulation of mammalian innate immune resistance to pathogens THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-01-21 US disclosed
US-20240417738-A1 IMMUNOTHERAPIES FOR THE TREATMENT OF CANCER OHIO STATE INNOVATION FOUNDATION 2024-12-19 US disclosed
EP-3484518-B1 ANTIBODY ADJUVANT CONJUGATES UNIV LELAND STANFORD JUNIOR (US) 2024-08-14 EP disclosed
CN-110234401-B Methods and compositions for adaptive immunomodulation 德克萨斯大学系统董事会 2024-03-01 CN disclosed
US-20240033348-A1 METHODS AND COMPOSITIONS FOR ADAPTIVE IMMUNE MODULATION Pulmotect, Inc. 2024-02-01 US disclosed
US-11826422-B2 Methods and compositions for adaptive immune modulation BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-11-28 US disclosed
EP-4218824-A2 IMMUNOCONJUGATE SYNTHESIS METHOD Bolt Biotherapeutics, Inc. (US) 2023-08-02 EP disclosed
US-20120082700-A1 COMPOSITIONS FOR STIMULATION OF MAMMALIAN INNATE IMMUNE RESISTANCE TO PATHOGENS THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2012-04-05 US disclosed
US-7560436-B2 Methods of treating gastrointestinal inflammation THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-07-14 US disclosed
US-20070004654-A1 Methods of treating gastrointestinal inflammation NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-01-04 US disclosed
US-7115622-B2 Amido ether substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-10-03 US disclosed
US-20050143413-A1 Amido ether substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2005-06-30 US disclosed
US-20040067975-A1 Amido ether substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2004-04-08 US disclosed
US-6664265-B2 Amido ether substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2003-12-16 US disclosed
US-20030187016-A1 Amido ether substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2003-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030187016-A1 Amido ether substituted imidazoquinolines IFNG, IRF3, EIF2AK2 TLR7 14/4885
US-20050143413-A1 Amido ether substituted imidazoquinolines IFNG, IRF3, EIF2AK2 TLR7 14/4885
US-20040067975-A1 Amido ether substituted imidazoquinolines IFNG, IRF3, EIF2AK2 TLR7 14/4885
US-20070004654-A1 Methods of treating gastrointestinal inflammation IFNG, IFNAR1, TNF TLR7 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.