Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935277 | 1.00 | MMP9 (0.60) | MMP9MMP8BCHELTA4HNPC1 | |
| SCHEMBL1071045 | 1.00 | MMP9 (0.60) | MMP9MMP8BCHELTA4HNPC1 | |
| SCHEMBL7398741 | 0.96 | MMP9 (0.55) | MMP9MMP8BCHELTA4HNPC1 | |
| SCHEMBL7398737 | 0.96 | MMP9 (0.55) | MMP9MMP8BCHELTA4HNPC1 | |
| SCHEMBL3073641 | 0.93 | MMP9 (0.60) | MMP9MMP8BCHELTA4HNPC1 | |
| SCHEMBL3288556 | 0.90 | MMP9 (0.69) | MMP9MMP8BCHELTA4H | |
| SCHEMBL1069240 | 0.90 | MMP9 (0.69) | MMP9MMP8BCHELTA4H | |
| SCHEMBL7395329 | 0.89 | NPC1 (0.53) | MMP9MMP8NPC1RAB9AMEN1 | |
| SCHEMBL9518560 | 0.89 | NPC1 (0.53) | MMP9MMP8NPC1RAB9AMEN1 | |
| SCHEMBL9129123 | 0.88 | FFAR1 (0.51) | MMP9MMP8BCHELTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |
| US-5391577-A | Active on central nervous system; antiepileptic agents | FARMITALIA CARLO ERBA S R L (IT) | 1995-02-21 | — | — | US | disclosed |
| US-5236957-A | Antiepileptic agents | FARMITALIA CARLO ERBA SRL (IT) | 1993-08-17 | — | — | US | disclosed |