Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8236713 | 0.89 | CHRM2 (0.52) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL9967271 | 0.89 | CHRM2 (0.52) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL9444152 | 0.87 | ALDH1A1 (0.53) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL7493133 | 0.80 | CHRM2 (0.42) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL4762996 | 0.80 | CHRM2 (0.42) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL4339192 | 0.80 | CHRM2 (0.42) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| Bromide SCHEMBL9298859 | 0.78 | CHRM2 (0.41) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL10368012 | 0.78 | CHRM2 (0.45) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL2421080 | 0.78 | ALDH1A1 (0.45) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL6990202 | 0.78 | CHRM2 (0.41) | CHRM2CHRM1MEN1CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338723-B1 | NOVEL COMPOUNDS | BEECHAM GROUP PLC (GB) | 1993-08-04 | — | — | EP | claimed |
| EP-0338723-A1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1989-10-25 | — | — | EP | claimed |
| US-5541194-A | PHARMACEUTICAL COMPOSTION USED TO TREAT DEMENTIA | BEECHAM GROUP P.L.C. (GB) | 1996-07-30 | — | — | US | disclosed |
| EP-0338723-B1 | NOVEL COMPOUNDS | BEECHAM GROUP PLC (GB) | 1993-08-04 | — | — | EP | disclosed |
| US-5217975-A | AZABICYCLIC COMPOUNDS FOR TREATING DEMENTIA | BEECHAM GROUP P.L.C. (GB) | 1993-06-08 | — | — | US | disclosed |
| US-5166357-A | Nitrogen heterocylic compounds used in treatment of dementia in mammals | BEECHAM GROUP P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| US-5110828-A | Treatment or prophylaxis of dementia | BEECHAM GROUP P.L.C. (GB) | 1992-05-05 | — | — | US | disclosed |
| EP-0402056-A2 | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them | Beecham Group p.l.c. (GB) | 1990-12-12 | — | — | EP | disclosed |
| US-4937239-A | Azabicycloalkane oxime & azabicycloalkene oxime muscarinic agents | WARNER-LAMBERT COMPANY (US) | 1990-06-26 | — | — | US | disclosed |
| EP-0366304-A2 | Heterocyclic derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1990-05-02 | — | — | EP | disclosed |
| EP-0338723-A1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1989-10-25 | — | — | EP | disclosed |
| EP-0322182-A2 | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1989-06-28 | — | — | EP | disclosed |