Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78835 | 0.98 | EPHX1 (0.48) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL11706920 | 0.88 | EPHX1 (0.45) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL15463389 | 0.88 | EPHX1 (0.45) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL29619546 | 0.88 | EPHX1 (0.45) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL29278260 | 0.86 | KDM4A (0.52) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL381501 | 0.86 | KDM4A (0.52) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL3271166 | 0.86 | KDM4A (0.52) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL1285950 | 0.84 | EPHX1 (0.50) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL139466 | 0.84 | KDM4A (0.54) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL23111738 | 0.83 | EPHX1 (0.48) | EPHX1CASP2ZDHHC20ZDHHC2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554699-A | USING BRANCHED N-ALKYLDITHIOCARBAMYL DERIVATIVE ACCELERATORS | THE B. F. GOODRICH COMPANY (US) | 1996-09-10 | — | — | US | claimed |