Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL217123 | 0.92 | ALDH1A1 (0.55) | ALDH1A1LMNAPKMGAATDP1 | |
| SCHEMBL14727179 | 0.92 | ALDH1A1 (0.55) | ALDH1A1LMNAPKMGAATDP1 | |
| SCHEMBL19892095 | 0.92 | ALDH1A1 (0.55) | ALDH1A1LMNAPKMGAATDP1 | |
| SCHEMBL8536518 | 0.88 | ALDH1A1 (0.51) | ALDH1A1LMNAPKMGAATDP1 | |
| SCHEMBL24048659 | 0.88 | ALDH1A1 (0.46) | ALDH1A1LMNAPKMGAATDP1 | |
| SCHEMBL24517406 | 0.87 | ALDH1A1 (0.50) | ALDH1A1LMNAPKMGAATDP1 | |
| SCHEMBL12924442 | 0.86 | ALDH1A1 (0.55) | ALDH1A1LMNAPKMGAATDP1 | |
| SCHEMBL9483425 | 0.86 | ALDH1A1 (0.55) | ALDH1A1LMNAPKMGAATDP1 | |
| SCHEMBL14063051 | 0.85 | ALDH1A1 (0.51) | ALDH1A1LMNAPKMGAATDP1 | |
| SCHEMBL29325087 | 0.85 | ALDH1A1 (0.51) | ALDH1A1LMNAPKMGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534250-A | METHYLENE DIESTER GROUPS, BIODEGRADABLE | NYCOMED IMAGING AS (NO) | 1996-07-09 | — | — | US | disclosed |
| EP-0547126-B1 | BIODEGRADABLE POLYMERS CONTAINING DIESTER UNITS | NYCOMED IMAGING AS (NO) | 1996-02-28 | — | — | EP | disclosed |