Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PPARA | Q07869 | 12/20 | 0.50 |
| ▸ | PPARG | P37231 | 10/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935675 | 1.00 | SMN1; SMN2 (0.58) | SMN1; SMN2PPARAPPARGL3MBTL1KDM4E | |
| SCHEMBL15333812 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2PPARAPPARGL3MBTL1KDM4E | |
| SCHEMBL8935648 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2PPARAPPARGKMT2A | |
| SCHEMBL8935645 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2PPARAPPARGKMT2A | |
| SCHEMBL7592846 | 0.81 | PPARG (0.74) | PPARAPPARG | |
| SCHEMBL8935705 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2PPARAPPARGL3MBTL1KMT2A | |
| SCHEMBL8935703 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2PPARAPPARGL3MBTL1KMT2A | |
| SCHEMBL8935787 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL3879629 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2PPARAPPARGKDM4EALDH1A1 | |
| SCHEMBL8935791 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |