Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | PPARA | Q07869 | 9/20 | 0.53 |
| ▸ | PPARG | P37231 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826322 | 1.00 | SMN1; SMN2 (0.64) | SMN1; SMN2PPARAPPARGLMNANPSR1 | |
| SCHEMBL7255301 | 0.87 | PPARG (0.64) | SMN1; SMN2PPARAPPARGLMNAHTT | |
| SCHEMBL28049294 | 0.87 | SMN1; SMN2 (0.54) | SMN1; SMN2PPARAPPARGNPSR1 | |
| SCHEMBL2280554 | 0.84 | SMN1; SMN2 (0.65) | SMN1; SMN2PPARAPPARGNPSR1HTT | |
| SCHEMBL4651839 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL295888 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL14122548 | 0.84 | LMNA (0.47) | SMN1; SMN2PPARAPPARGLMNANPSR1 | |
| SCHEMBL14121890 | 0.84 | LMNA (0.47) | SMN1; SMN2PPARAPPARGLMNANPSR1 | |
| SCHEMBL14121887 | 0.84 | LMNA (0.47) | SMN1; SMN2PPARAPPARGLMNANPSR1 | |
| SCHEMBL30475592 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2PPARAPPARGLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |