Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.64 |
| ▸ | PPARA | Q07869 | 14/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935658 | 1.00 | PPARG (0.64) | PPARGPPARASMN1; SMN2MAPTTP53 | |
| SCHEMBL8384349 | 0.92 | PPARG (0.56) | PPARGPPARASMN1; SMN2MAPTTP53 | |
| SCHEMBL2106689 | 0.86 | PPARG (0.63) | PPARGPPARASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL28745487 | 0.86 | PPARG (0.63) | PPARGPPARASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL11550284 | 0.85 | SMN1; SMN2 (0.67) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL9983415 | 0.85 | PPARG (0.51) | PPARGPPARASMN1; SMN2MAPTTP53 | |
| SCHEMBL8806421 | 0.84 | PPARG (0.50) | PPARGPPARASMN1; SMN2MAPTTP53 | |
| SCHEMBL8935859 | 0.84 | SMN1; SMN2 (0.70) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL433427 | 0.84 | SMN1; SMN2 (0.65) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL21991991 | 0.84 | PPARG (0.66) | PPARGPPARASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1260266-C | Poly(hydroxy alkanoate), its preparation method and use of microbe in its preparation | CANON KK (JP) | 2006-06-21 | — | — | CN | disclosed |
| CN-1321695-A | Poly(hydroxy alkanoate), its preparation method and use of microbe in its preparation | CANON KK (JP) | 2001-11-14 | — | — | CN | disclosed |
| CN-1070487-C | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 2001-09-05 | — | — | CN | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| CN-1098099-A | The hexahydro naphthalene ester derivative, their preparation and their treatment are used | SANKYO CO (JP) | 1995-02-01 | — | — | CN | disclosed |
| US-4297516-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| EP-0002590-B1 | NOVEL PROSTAGLANDIN COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN CYANAMID COMPANY (US) | 1981-09-30 | — | — | EP | disclosed |
| US-4254285-A | 1-Hydroxymethyl-1-1-oxo prostane derivatives of the E and F series | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4235797-A | CHEMICAL INTERMEDIATES FOR PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4218566-A | BRONCHODILATORS, ANTIINFLAMMATORY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-08-19 | — | — | US | disclosed |
| US-4202822-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1980-05-13 | — | — | US | disclosed |
| US-4197245-A | 1-Hydroxymethyl-1-oxo-prostane derivatives of the A1 series | AMERICAN CYANAMID COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
| US-4189597-A | PROSTAGLANDINS, BRONCHODILATORS | AMERICAN CYANAMID COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| US-4172839-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1979-10-30 | — | — | US | disclosed |
| US-4170597-A | 1-Hydroxymethyl-1-oxo-prostane derivatives of the E2 series | AMERICAN CYANAMID COMPANY (US) | 1979-10-09 | — | — | US | disclosed |
| US-4165331-A | PROSTAGLANDINS/AND DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| EP-0002590-A1 | Novel prostaglandin compounds, processes for the preparation thereof and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-06-27 | — | — | EP | disclosed |
| US-4154959-A | 11-(2-Hydroxyethylthio)prostenoic acid E series derivatives | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4154954-A | BRONCHODILATOR AGENTS; ANTIINFLAMMATORY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4085272-A | BRONCHODILATORS, INFLAMMATORY MEDEATOR RELEASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-04-18 | — | — | US | disclosed |