Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | PPARG | P37231 | 18/20 | 0.60 |
| ▸ | PPARA | Q07869 | 17/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1171344 | 1.00 | SMN1; SMN2 (0.70) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL8935844 | 1.00 | SMN1; SMN2 (0.70) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL11550284 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL4257140 | 0.86 | PPARG (0.65) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL29217238 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL11128486 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL21991991 | 0.85 | PPARG (0.66) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL1745447 | 0.85 | PPARG (0.66) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL433427 | 0.85 | SMN1; SMN2 (0.65) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL9656236 | 0.85 | SMN1; SMN2 (0.65) | SMN1; SMN2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070487-C | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 2001-09-05 | — | — | CN | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |