Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935695 | 1.00 | KMT2A (0.66) | KMT2AGAACYP1A2CYP2C9PKM | |
| SCHEMBL8434636 | 0.85 | KMT2A (0.47) | KMT2ACYP1A2CYP2C19TSHRL3MBTL1 | |
| SCHEMBL11587287 | 0.81 | KMT2A (0.76) | KMT2AGAACYP1A2CYP2C9PKM | |
| SCHEMBL6449650 | 0.81 | KMT2A (0.47) | KMT2AGAACYP1A2CYP2C9PKM | |
| SCHEMBL5861162 | 0.80 | SMN1; SMN2 (0.46) | KMT2ATSHRL3MBTL1MEN1LMNA | |
| SCHEMBL10693344 | 0.79 | KMT2A (0.68) | KMT2AGAACYP1A2CYP2C9PKM | |
| SCHEMBL8468151 | 0.79 | KMT2A (0.68) | KMT2AGAACYP1A2CYP2C9PKM | |
| SCHEMBL8935823 | 0.79 | KMT2A (0.68) | KMT2AGAACYP1A2CYP2C9PKM | |
| SCHEMBL5721832 | 0.79 | KMT2A (0.68) | KMT2AGAACYP1A2CYP2C9PKM | |
| SCHEMBL12310141 | 0.79 | KMT2A (0.68) | KMT2AGAACYP1A2CYP2C9PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |