Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.62 |
| ▸ | PPARA | Q07869 | 9/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846721 | 1.00 | PPARG (0.62) | PPARGPPARAGAACYP1A2CYP2C9 | |
| SCHEMBL17904962 | 1.00 | PPARG (0.62) | PPARGPPARAGAACYP1A2CYP2C9 | |
| SCHEMBL7966234 | 0.90 | CYP1A2 (0.71) | PPARGPPARAGAACYP1A2CYP2C9 | |
| SCHEMBL1933913 | 0.87 | CYP1A2 (0.53) | PPARGPPARAGAACYP1A2CYP2C9 | |
| SCHEMBL11322441 | 0.87 | CYP1A2 (0.53) | PPARGPPARAGAACYP1A2CYP2C9 | |
| SCHEMBL11715391 | 0.86 | TAS1R3 (0.55) | PPARGPPARAGAACYP1A2CYP2C9 | |
| SCHEMBL11708010 | 0.86 | PPARG (0.53) | PPARGPPARAGAACYP1A2CYP2C9 | |
| SCHEMBL11519130 | 0.86 | PPARG (0.53) | PPARGPPARAGAACYP1A2CYP2C9 | |
| SCHEMBL27450538 | 0.86 | GAA (0.55) | PPARGPPARAGAACYP1A2CYP2C9 | |
| SCHEMBL4744796 | 0.86 | GAA (0.55) | PPARGPPARAGAACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |