SCHEMBL8935879

SCHEMBL8935879

CC[C@H](Oc1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 19/20 0.68
PPARG P37231 18/20 0.68
SMN1; SMN2 Q16637 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3028298 1.00 PPARA (0.68) PPARAPPARGSMN1; SMN2
SCHEMBL9320814 0.95 PPARA (0.65) PPARAPPARGSMN1; SMN2
Hydrochloric Acid SCHEMBL9362380 0.94 PPARA (0.63) PPARAPPARGSMN1; SMN2
Maleic Acid SCHEMBL6261359 0.92 PPARA (0.59) PPARAPPARGSMN1; SMN2
SCHEMBL11458229 0.92 PPARA (0.68) PPARAPPARGSMN1; SMN2
Fumaric Acid SCHEMBL6261366 0.92 PPARA (0.59) PPARAPPARGSMN1; SMN2
SCHEMBL30575128 0.86 PPARA (0.55) PPARAPPARG
SCHEMBL10875312 0.86 PPARA (0.66) PPARAPPARG
SCHEMBL8124439 0.86 PPARA (0.54) PPARAPPARG
SCHEMBL11550284 0.85 SMN1; SMN2 (0.67) PPARAPPARGSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731200-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD Pharma A/S (DK) 2026-04-29 EP claimed
WO-2024261020-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD PHARMA A/S (DK) 2024-12-26 WO claimed
EP-3723745-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2020-10-21 EP claimed
CN-111587109-A Phenoxy acids for the treatment of neuromuscular disorders NMD制药股份公司 2020-08-25 CN claimed
US-20190183833-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA APS 2019-06-20 US claimed
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US claimed
WO-2019115777-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2019-06-20 WO claimed
EP-4731200-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD Pharma A/S (DK) 2026-04-29 EP disclosed
WO-2024261020-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD PHARMA A/S (DK) 2024-12-26 WO disclosed
US-11730714-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-08-22 US disclosed
US-11730714-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-08-22 US disclosed
US-11147788-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2021-10-19 US disclosed
EP-3723745-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2020-10-21 EP disclosed
CN-111587109-A Phenoxy acids for the treatment of neuromuscular disorders NMD制药股份公司 2020-08-25 CN disclosed
US-20190183833-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA APS 2019-06-20 US disclosed
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US disclosed
WO-2019115777-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2019-06-20 WO disclosed
US-5491167-A INHIBITORS OF CHOLESTEROL BIOSYNTHESIS SANKYO COMPANY, LIMITED (JP) 1996-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11730714-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, RYR2 PPARA 3247/4885PPARG 3332/4885SMN1; SMN2 13/4885
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 PPARA 3247/4885PPARG 3332/4885SMN1; SMN2 13/4885
US-11147788-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, RYR2 PPARA 3247/4885PPARG 3332/4885SMN1; SMN2 13/4885
US-20190183833-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 PPARA 3247/4885PPARG 3332/4885SMN1; SMN2 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.