SCHEMBL11458229

SCHEMBL11458229

CCC(Oc1ccc(Cc2ccc(Cl)cc2)cc1)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 19/20 0.68
PPARG P37231 18/20 0.68
SMN1; SMN2 Q16637 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8935879 0.92 PPARA (0.68) PPARAPPARGSMN1; SMN2
SCHEMBL3028298 0.92 PPARA (0.68) PPARAPPARGSMN1; SMN2
SCHEMBL9320814 0.88 PPARA (0.65) PPARAPPARGSMN1; SMN2
Hydrochloric Acid SCHEMBL9362380 0.86 PPARA (0.63) PPARAPPARGSMN1; SMN2
Fumaric Acid SCHEMBL6261366 0.85 PPARA (0.59) PPARAPPARGSMN1; SMN2
Maleic Acid SCHEMBL6261359 0.85 PPARA (0.59) PPARAPPARGSMN1; SMN2
SCHEMBL8935911 0.82 PPARG (0.71) PPARAPPARGSMN1; SMN2
SCHEMBL8935920 0.82 PPARG (0.71) PPARAPPARGSMN1; SMN2
SCHEMBL10967275 0.81 EPHX2 (0.64) PPARAPPARG
SCHEMBL11641221 0.81 PPARG (0.61) PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4182902-A P-(P'-CHLOROBENZYL) PHENOXYACETIC ACID SIEGFRIED AKTIENGESELLSCHAFT (CH) 1980-01-08 US disclosed