Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4581970 | 0.68 | L3MBTL1 (0.48) | SMN1; SMN2L3MBTL1TSHRKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8936066 | 0.68 | GAA (0.31) | GAA | |
| SCHEMBL14538070 | 0.65 | TSHR (0.46) | SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL8524128 | 0.65 | PIK3CD (0.46) | SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL2228403 | 0.65 | TSHR (0.51) | SMN1; SMN2L3MBTL1TSHRALDH1A1KMT2A | |
| SCHEMBL9921226 | 0.64 | L3MBTL1 (0.44) | SMN1; SMN2L3MBTL1KMT2AMEN1RAB9A | |
| SCHEMBL20579542 | 0.64 | L3MBTL1 (0.47) | SMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL8936001 | 0.64 | SMN1; SMN2 (0.37) | SMN1; SMN2TSHRALDH1A1KMT2AHPGD | |
| SCHEMBL27418304 | 0.64 | KMT2A (0.51) | SMN1; SMN2L3MBTL1TSHRALDH1A1KMT2A | |
| SCHEMBL312170 | 0.63 | KMT2A (0.50) | TSHRKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486531-A | ANGINA, HYPOTENSIVE AGENTS, ERECTILE DYSFUNCTION | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-01-23 | — | — | US | disclosed |