Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11150308 | 0.75 | ALDH1A1 (0.54) | ALDH1A1ACHE | |
| SCHEMBL19176798 | 0.66 | SMN1; SMN2 (0.48) | HTTLMNAALDH1A1L3MBTL1TSHR | |
| SCHEMBL162819 | 0.65 | KDM4E (0.50) | HTTL3MBTL1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL19176808 | 0.65 | KDM4E (0.50) | HTTALDH1A1L3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL16088178 | 0.65 | KMT2A (0.54) | HTTALDH1A1L3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL23990643 | 0.64 | CA12 (0.46) | ALDH1A1L3MBTL1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL2352841 | 0.64 | HTT (0.47) | HTTLMNAALDH1A1L3MBTL1TSHR | |
| SCHEMBL10245956 | 0.64 | SMN1; SMN2 (0.49) | HTTLMNAALDH1A1L3MBTL1TSHR | |
| SCHEMBL2352832 | 0.63 | TSHR (0.55) | HTTALDH1A1L3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL23989979 | 0.63 | CA12 (0.44) | HTTL3MBTL1TSHRSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486531-A | ANGINA, HYPOTENSIVE AGENTS, ERECTILE DYSFUNCTION | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-01-23 | — | — | US | disclosed |